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Anal Sac Adenocarcinoma in Dogs: Astro’s Surgery and Treatment

Brown and white dog holding a yellow toy in its mouth on a green lawn.

It Started With A Change in Behaviour

Astro’s family knew something wasn’t quite right. Their 10-year-old Border Collie cross was losing weight despite having a big appetite, drinking far more than usual and had started behaving differently around food.

But Astro has never been particularly keen on veterinary examinations. He’s much happier at home with his family, where he takes his role looking after the younger children very seriously. So when he first came to see Dr Joyce, we had to keep his examination brief, and then we arranged for him to return the following day after medication to help him feel calmer.

His second visit, unfortunately, revealed a much more serious problem than his family had expected.

“Astro’s family knew something wasn’t quite right. He was losing weight despite having a big appetite and drinking far more than usual.”

An Unexpected Result in Astro’s Blood Tests

On Astro’s return, he was much happier and calm enough for Dr Perin to assess him and take some blood samples.

One thing that immediately stood out was his calcium level being very high at 3.62 mmol/L. This helped explain why he had been drinking and urinating so much, but it also raised concerns about an underlying cancer.

A rectal examination found a large, misshapen mass associated with Astro’s right anal sac, around two-thirds the size of an apricot. His medial iliac lymph nodes, which sit internally between the colon and spine, were also enlarged. This raised concern that the disease may already have spread beyond the primary tumour.

The likely diagnosis was anal sac adenocarcinoma.

Making a Difficult Decision About Surgery

This was serious news for Astro’s family. His excessive drinking, weight loss and changes in behaviour were already affecting his quality of life, and without treatment, his outlook was not good.

Surgery to remove the primary tumour, followed by treatment with a new generation chemotherapy for dogs with certain cancers, was put forward as an option. Dr Perin discussed both the potential benefits and the significant risks associated with operating in this area, including faecal incontinence, bowel damage and wound complications.

After taking a couple of days to consider, Astro’s family decided they weren’t ready to lose him.

Astro returned for surgery, where Dr Perin carefully removed the right anal sac and associated tumour. His anaesthetic remained stable throughout the procedure, his recovery was routine and he was able to go home that afternoon.

Testing of the removed tissue confirmed that Astro had an anal sac adenocarcinoma. His treatment plan was to begin chemotherapy after surgery, with his family able to give the tablets to him at home three times a week. It didn’t take long for everyone to notice a change.

Within days of surgery, Astro’s constant drinking had reduced towards normal. At his wound check just over two weeks later, his family reported that the excessive thirst had stopped almost immediately after the primary tumour was removed. He had also perked up enormously and was much more active around the house.

“A few months after a diagnosis that could have taken him from his family very quickly, Astro is back to enjoying a normal life at home.”

Brown and white dog crouched in the grass looking intently at an orange ball in the foreground.

Living With Cancer After Surgery

Removing Astro’s primary tumour was only one part of his treatment. Because his internal lymph nodes were already enlarged, chemotherapy was continued with the aim of keeping the remaining disease stable.

At his next recheck, Astro was taking the medication without any noted side effects. His stools were normal, he was back to his usual self and his surgical site had healed well.

Importantly, his enlarged lymph nodes had not increased in size. Dr Perin assessed his disease as stable, so the decision was made to continue with the existing treatment.

Astro’s family will now keep an eye on his drinking and his stools at home. Changes in stool width can sometimes indicate that enlarged internal lymph nodes are placing pressure on the colon, so this gives another useful way to monitor him between veterinary checks.

Back to Being Astro

Astro’s cancer hasn’t disappeared. He will need ongoing treatment and monitoring. But a few months after a diagnosis that could have taken him from his family very quickly, he is back to enjoying a normal life at home.

For a dog who would much rather avoid veterinary attention altogether, Astro has been through a lot. Careful use of medication before his visits has allowed us to examine and monitor him without putting him through unnecessary stress, while his family have taken on his ongoing treatment at home.

Frequently Asked Questions

What are the signs of anal sac adenocarcinoma in dogs?

Signs can vary. In Astro’s case, weight loss despite a big appetite, excessive drinking and urination and changes in his behaviour around food led his family to seek veterinary advice.

Can anal sac adenocarcinoma cause excessive thirst in dogs?

Yes. Astro had a very high calcium level, which helped explain his excessive drinking and urination. The abnormal result also raised concerns that an underlying cancer could be responsible.

How is anal sac adenocarcinoma diagnosed in dogs?

Astro’s anal sac mass was found during a rectal examination after his blood tests showed a very high calcium level. Testing of the tumour after its surgical removal confirmed anal sac adenocarcinoma.

How is anal sac adenocarcinoma treated in dogs?

Treatment depends on the individual dog and their disease. Astro underwent surgery to remove his right anal sac and primary tumour, followed by ongoing treatment with Palladia, a chemotherapy medication.

Can dogs live with anal sac adenocarcinoma after surgery?

Astro still has cancer and requires ongoing treatment and monitoring. At his follow-up, his enlarged lymph nodes had not increased in size, his disease was considered stable and he was back to his usual self.